WebOct 24, 2014 · Uromodulin (UMOD)/Tamm-Horsfall protein, the most abundant human urinary protein, plays a key role in chronic kidney diseases and is a promising therapeutic … WebTamm-Horsfall glycoprotein also known as uromodulin is used as a standard for calibration of uromodulin in urine samples. Store at 2-8°C. Order online. ... This protein consists of three epidermal growth factor (EGF) domains and a zona pellucida-like domain. THGP is a member of the glycosylphosphatidylinositol (GPI) protein family and is ...
The role of Tamm-Horsfall protein in the pathogenesis of reflux ...
WebTamm-Horsfall protein (TH protein), a renal epithelial glycoprotein, was isolated originally from human urine [1, 2]. This membrane glycoprotein has several unusual physicochemical characteristics that may determine its role in normal tubular function in its distal nephron site of synthesis and in pathologic conditions. Variations of the ionic environment in the … WebApr 1, 2024 · Mutations in the uromodulin gene decrease urinary excretion of Tamm-Horsfall protein. Kidney Int. 2004;66:974–977. doi: 10.1111/j.1523-1755.2004.00845.x. El-Achkar TM, McCracken R, Rauchman M, Heitmeier MR, Al-Aly Z, Dagher PC, Wu XR. Tamm-Horsfall protein-deficient thick ascending limbs promote injury to neighboring S3 segments in an … cool pool paint for concrete
The presence in serum of proteins which are immunologically cross …
WebDec 16, 2008 · What is its function? 1. Tamm-Horsfall protein acts as a constitutive inhibitor of calcium-based stone formation. Mice deficient for Tamm-Horsfall protein show an increased tendency towards nephrolithiasis. 2. Tamm-Horsfall protein acts to prevent urinary tract infection. WebOct 24, 2014 · Uromodulin (UMOD)/Tamm-Horsfall protein, the most abundant human urinary protein, plays a key role in chronic kidney diseases and is a promising therapeutic target for hypertension. WebTraductions en contexte de "Tamm-Horsfall proteins" en anglais-français avec Reverso Context : Finally, tubular secretion of proteins, particularly of Tamm-Horsfall proteins, is exceptionally recovered. family support fund application