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NettetINCB 086550;INCB-086550; Formula: C41H39N7O4: M. Wt: 693.81: Biological Activity; Description: PD-L1 inhibitor INCB086550 specifically targets PD-L1 expressed on … NettetINCB086550 selectively inhibited PD-L1 with IC50 of 3.1 nM, 4.9 nM and 1.9 nM for human, rhesus monkey and rat pD-L1, respectively. INCB086550 could not inhibit the binding of PD-L2 to PD-1 at 10 μM. INCB086550 significantly inhibits the PD-1/PD-L1 signaling axis by binding to PD-L1 protein, leading to PD-L1 dimerization and … Nettet8. nov. 2024 · Note 1: VIH is the high level voltage for IS32FL3265A’s SDA, SCL and INTB, which is usually same as VCC pin and VCC of Micro Controller, e.g. if VCC of Micro Controller is 3.3V, VCC(IS32FL3265A)=V IH =3.3V,if VCC of Micro Controller is 5V, VCC(IS32FL3265A)=V IH =5V, but magic cherry