Web15 dec. 2024 · Using a recently engineered plasmid design that enables the synthesis of complex ferritin nanostructures with specific H to L subunit ratios, we show that homopolymer L and heteropolymer L-rich ferritins have a remarkable hyperthermostability (Tm = 115 ± 1°C) compared to their H-ferritin homologues (Tm = 93 ± 1°C). WebWe found that the CutA1 protein, from Pyrococcus horikoshii (PhCutA1), has an extremely high denaturation temperature (T d) of nearly 150 °C, which exceeds the highest record determined by DSC by about 30 °C. To elucidate the mechanism of the ultra-high stability of PhCutA1, we analyzed the crystal structures of CutA1 proteins from three different …
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WebThe 2-haloacid dehalogenases (EC 3.8.1.X) are industrially important enzymes that catalyze the cleavage of carbon–halogen bonds in 2-haloalkanoic acids, releasing halogen ions and producing corresponding 2-hydroxyl acids. These enzymes are of particular interest in environmental remediation and environmentally friendly synthesis of optically pure … WebHA2 contains fusion peptide (FP), soluble ectodomain (SE), transmembrane (TM), and intraviral domains with respective lengths of ∼ 25, ∼ 160, ∼ 25, and ∼ 10 residues. The … supprimer jdk mac
Structural and genomic correlates of hyperthermostability
Web12 jul. 2007 · Thus, compactness of EstE1 structure provides a plausible explanation for its hyperthermostability. Thermostability determinants of EstE1 identified in this study and in our previous work [ 5 ] altogether suggest that EstE1 might be originated from a hyperthermophilic archaeon because its thermostability mainly relies on the "structure … Web1 dec. 2011 · In conclusion, thermostable BGLPf has a comparatively large solvent-inaccessible area at the A–C interface; the averaged solvation free energy is reduced, thereby providing the A–C dimer with hyperthermostability. These results suggest that in BGLs the A–C dimer is more stable than the A–B dimer. WebUehara, R. et al., Requirement of Ca(2+) Ions for the Hyperthermostability of Tk-Subtilisin from Thermococcus kodakarensis. Biochemistry (2012) Release Date 2012-07-11 Peptides Tk-subtilisin: A SMTL:PDB supprimer git d'un projet