Cisplatin and breast cancer
WebJun 15, 2024 · Introduction. As one of the main causes of female deaths, breast cancer (BC) is a heterogeneous tumor with different subtypes [1,2].Triple negative breast cancer (TNBC) is the most invasive subtype with a relatively poor prognosis, because it lacks targeted therapies and has a low response to chemotherapy [3,4].Moreover, the disease … WebCisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain Metastases The safety and scientific validity of this study is the responsibility of the study sponsor and investigators.
Cisplatin and breast cancer
Did you know?
WebMar 25, 2024 · Here, we report that RRS1 is associated with cisplatin resistance in breast cancer cells. RRS1 silencing increased the sensitivity of MCF-7/DDP cells to cisplatin and inhibited cancer cell proliferation by blocking cell cycle distribution and enhancing apoptosis. AEG-1 (astrocyte elevated gene-1) promotes drug resistance by interfering with the ... WebMay 26, 2024 · Neither gemcitabine nor cisplatin affected berzosertib PK. Most patients in both arms achieved a best response of either partial response or stable disease. ... E. R. Triple-negative breast cancer ...
WebHere we aim to study the effect of cisplatin at different doses on breast cancer growth and metastasis. Methods: We used cisplatin to treat breast cancer cells, then detected the … http://www.bccancer.bc.ca/chemotherapy-protocols-site/Documents/Breast/BRAVGEMP_Protocol.pdf
WebApr 13, 2024 · Increasing WNT7A synthesis by invasive cancer cells in breast cancer may improve TGF ... Polanska HH, Vaculovic T, et al. Sensitivity to cisplatin in head and neck cancer cells is significantly ... WebOct 5, 2014 · Cisplatin and Breast Cancer Breast cancer is one of the leading causes of women mortality worldwide. Chemotherapy is the only option for treating the malignant …
WebApr 1, 1993 · Pharmacological studies on breast cancer can be cited to Cisplatin [12] .Cisplatin is one of the factors used in chemotherapy; and yet, it is not always used to treat breast...
WebApr 12, 2024 · The long-term prognosis for women with recurrent endometrial cancer is also poor. The combination of the chemotherapy drugs cisplatin and paclitaxel has long been the standard treatment for women with advanced or recurrent endometrial cancer. But treatment options for these two groups of patients have changed recently, largely … philip celentano berkshire eagleWebNov 4, 2024 · Cisplatin is a DNA-intercalating agent that cross-links DNA resulting in interference with RNA transcription and DNA replication activities. If the DNA lesions are … philip cefaiWebHere is what the Women's Cancer Center says about it. "Carboplatin is now being used more often than cisplatin because it can be given on an outpatient basis. It causes less kidney damage, hearing loss, nausea and vomiting and peripheral nerve damage (manifested by muscle weakness and numbness or tingling). philipchalk \\u0026 associatesphilip cessac pearlandrentalsWeb2 days ago · Cisplatin is used successfully in the chemotherapy of testicular cancer. However, patients who develop resistance to the cytostatic drug urgently need … philip cederqvistWeb2.3 Advanced Ovarian Cancer . Cisplatin for injection has been administered at 75 mg/m. 2 . to 100 mg/m. intravenously per cycle once every 3 to 4 weeks on Day 1. Other doses and combination regimens have been used. 2.4 Advanced Bladder Cancer . Cisplatin for injection has been administered at 50 mg/m. 2 . to 70 mg/m. intravenously per cycle philipchalk and associatesWebTriple-negative breast cancer (TNBC) is a highly aggressive type of breast cancer lacking estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor2 (HER2), which resulted in the lack of target for treatment. 14 Up to date, drug treatment for triple-negative breast cancer still limited to cytotoxic agents such as ... philip chalmers bp